WebThis led to the identification of a third case with a possibly damaging missense mutation in ATP1A3 and three others cases with predicted pathogenic missense variants in the … WebTransmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.

FXYD family - Wikiwand

WebJan 21, 2003 · Recently, a regulatory mechanism was defined that is mediated by interaction of Na,K-ATPase with small proteins of the FXYD family, which possess a single … WebPharos : Target Details - FXYD5 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data highest rated robotic vacuum cleaner

FXYD5 Protein Has a Pro-inflammatory Role in Epithelial Cells

WebThis gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. WebThe goal of the present study was to elucidate the potential role of FXYD8, a member of the fish FXYD protein family, in the modulation of NKA activity in the kidneys of this euryhaline pufferfish ... WebAug 8, 2002 · A family of small, single-span membrane proteins (the FXYD family) has recently been defined based on their sequence and structural homology. Some members of this family have already been identified as tissue-specific regulators of Na,K-ATPase (NKA). highest rated roguelike