WebBy inhibiting the release of neurotransmitters, a drug can indirectly reduce overall receptor activity by decreasing the quantity of neurotransmitter in the synapse. A presynaptic regulator binds to the autoreceptors on the presynaptic neuron and inhibits neurotransmitter release (see diagram below). WebJul 27, 2024 · Causes of Death. Another major difference between cocaine and heroin is their cause of death in users. Because cocaine increases alertness as well as activity in the heart, most cocaine users die specifically from cardiotoxicity. Cardiotoxicity is when the heart muscle is so damaged that it’s unable to pump blood throughout the body as it ...
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